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Yaz, Yasmin Among Birth Control Pills with Higher Blood Clot Risk

Some birth control pills, including the popular Yaz and Yasmin, carry a higher risk of blood clots compared with some others, according to a new study published in the British Medical Journal.

According to The Globe and Mail, the study was led by Frits Rosendaal of the department of clinical epidemiology at Leiden University Medical Centre in the Netherlands. Over 1,500 women who suffered blood clots in their legs or their lungs while taking oral contraceptives were compared with more than 1,700 women of similar backgrounds who did not suffer blood clots.

The researchers found that oral contraceptives with the lowest amount of estrogen carried the lowest risk of blood clots. However, the type of progestin a pill contained also made a difference. For instance, pills made with drospirenone, such as Yasmin and Yaz, showed a 6.3-fold increase in risk of blood clots. The highest risk was seen among users of oral contraceptives that used desogestrol, which had 7.3 times the risk of blood clots. Contraceptive pills containing levonorgestrel, however, increased the risk of clots by only 3.6-fold, The Globe and Mail said. All of the pills studied were effective in preventing pregnancy.

In October 2008, the U.S. Food & Drug Administration (FDA) cited two Yaz commercials for deceptive claims. In a warning letter, the FDA faulted Bayer, the drug? smaker, for overstating the benefits of Yaz. The FDA also criticized the ads for containing fast-moving images and background music that might be distracting to viewers. These elements were aired while information about potential Yaz side effects ? including blood clots ? was described. The FDA warning letter said the television commercials minimized the risks posed by Yaz.

Bayer ended up pulling the misleading ads. It also reached an agreement with the FDA and 27 state attorneys general to run new TV spots correcting the misinformation from the pulled commercials. They began running in early 2009.

FDA warnings -The makers of Yaz and Yasmin have been warned about their marketing.

In 2003, the FDA warned Berlex Laboratories, which has since been purchased by Bayer, about TV ads which used the tagline: ?Ask about Yasmin and the difference a little chemistry can make.?


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About The Author

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Laura Hack

Laura Hack is a paralegal with Terrell • Hogan. She has been with the firm since 1996 and has worked primarily for Wayne Hogan. She is an experienced Paralegal with 30+ years of working in the law practice industry. Skilled in Appeals, Civil Trial Litigation Support, Torts, Trial Practice, and Pleadings.