In pharmacology, bisphosphonates is a class of drugs that inhibits the resorption of bone, which is the organic process in which the body breaks down and reabsorbs the bone.Its uses include the prevention and treatment of osteoporosis, osteitis deformans (“Paget’s disease of bone”), bone metastasis, multiple myeloma and other conditions that feature bone fragility.Stronger forms of bisphosphonates are commonly used in the management of advanced cancers that have metastasized to the bone, where the disease often causes bone pain and possibly even fractures.Several cancers can involve or metastasize to the bone, including lung cancer, breast cancer, prostate cancer, multiple myeloma and others.When bisphosphonates are given in cancer chemotherapy, the drugs are given intravenously and usually for extended periods of time.