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Oral surgeons have described ONJ as a condition in which the bone tissue fails to heal (osteo/bone and necrosis/death) after dental trauma, including tooth extrac­tions, oral surgery and other common dental proce­dures.ONJ can cause chronic pain, dysfunction and disfig­urement. Though current treat­ments involve long-term antibi­otics therapy and surgical removal of the dead bone, there is […]

While trying to quantify the exact number of people poten­tially affected is difficult, Fosamax alone is taken by nearly 10 million men and women.- Since 2001, more than 2,400 patients taking bispho­s­pho­nates have reported jaw bone death. Most of these reports came from people who took potent, intra­venously delivered versions of these drugs — An […]

Bispho­s­pho­nates have been linked to several side effects. The most common from bispho­s­pho­nates taken orally are upset stomach and erosion of the esophagus, and in fewer circum­stances are believed to be linked to Osteonecrosis of the jaw (ONJ) also referred to as dead jaw. Victims generally develop severe abscesses around the mouth, painful toothaches and […]

Due to the favorable climate and terrain, many Floridians use bicycles as a source of recre­ation and enjoyment. However, bicyclists should be aware of traffic condi­tions where they are required to ride on the roadway.Bicycle riders less than age (16) must wear a safety helmet and bicycles on the roadway have most of the same […]

Mar 13, 2005 | Rita Rubin | USA TODAY Salvatore Ruggiero was puzzled.Over a three-year period, the jaws of dozens of patients who had undergone oral surgery at his hospital had failed to heal properly. Part of the jawbone had died and become exposed.We never saw this before in the jaw except in patients who […]

(06/02/06)The New York Times By GINA KOLATA Published: June 2, 2006 In the last 10 years, millions of patients have taken a class of drugs that can prevent agonizing broken and deteri­o­rating bones. The drugs once seemed perfectly safe and have trans­formed life for patients with cancer or osteo­porosis. But recently there have been reports […]

(05/02/06)It is important for dentists to be aware that while on treatment, invasive dental proce­dures should be avoided if at all possible. Dentists should be made aware of a patient’s medical history, current medica­tions and any treat­ments (current or past) using intra­venous bispho­s­pho­nates because of their long half-life (period of time that the drugs stay […]

Did you ever notice when you blow in a dog’s face he gets mad at you? But when you take him in a car he sticks his head out the window!” -Steve Bluestone Although dogs share our homes, dogs are still animals and not humans. While they often make wonderful family pets, they can also […]

(05/02/06)The most commonly prescribed brands of bispho­s­pho­nates include:- Fosamax manufac­tured by Merck- Aredia and Zometa manufac­tured by Novartis- Actonel and Didronel manufac­tured by Proctor & Gambel- Boniva manufac­tured by Roche Labora­­tories- Skelid (generic name is tiludronate) manufac­tured by Sanofi Winthrop Indus­tries- Bonefos manufac­tured by Schering  

In pharma­cology, bispho­s­pho­nates is a class of drugs that inhibits the resorption of bone, which is the organic process in which the body breaks down and reabsorbs the bone.Its uses include the prevention and treatment of osteo­porosis, osteitis deformans (“Paget’s disease of bone”), bone metas­tasis, multiple myeloma and other condi­tions that feature bone fragility.Stronger forms […]